A Perth man has been arrested as part of a mass mafia crackdown across Europe.

Police across the continent have arrested at least 84 suspected mobsters and seized around 2 million euros ($A3.1 million) in co-ordinated raids targeting a powerful branch of the Italian mafia on Wednesday.

Domenico Condo - who was born in Mt Lawley - is among those arrested.

Mr Condo is also the subject of an outstanding arrest warrant from WA Police.

The 38-year-old was arrested in Germany allegedly with a quantity of drugs.

The raids in Germany, Italy, Belgium and the Netherlands are the culmination of an investigation codenamed Pollino that was launched in 2016 against the ’ndrangheta criminal group on allegations of cocaine trafficking, money laundering, bribery and violence.

The operation was co-ordinated by Eurojust, the European prosecution agency that fights cross-border organised crime.

Eurojust said the massive operation was the biggest of its kind in Europe.

Four tonnes of cocaine were traced during the two-year joint investigation, while cocaine and ecstasy pills were seized in Wednesday’s raids.

Federico Cafiero De Raho, Italy's Anti-Mafia and Anti-terrorism national prosecutor meets the media during a press conference in Rome. Picture: AP

Federico Cafiero De Raho, Italian anti-mafia and anti-terrorism national prosecutor, sounded a note of caution, saying the raids only scratched the surface of the powerful ’ndrangheta, whose tentacles and illicit activities spread all over the world.

Speaking in The Hague, De Raho said the arrests are “nothing” for the ’ndrangheta group.

“There are thousands of people who should be arrested and billions of euros that should be seized,” he said.

Police Commissioner Chris Dawson said WA Police had also been seeking Domenico Condo over serious drugs and weapons offences.

“I can confirm that Mr Domenico Condo has some arrest warrants in WA, he is wanted in this State for a number of drug trafficking charges,” Mr Dawson said. “He’s also wanted for possession of a sub-machine gun and pill press. “In that sense we will be working very closely with the Drug Enforcement Administration and international policing bodies and we will be seeking extradition in due course.”

Mr Dawson said WA Police had been “actively pursuing” the former Perth man.

“I’m advised that the WA Police did seek some assistance from the DEA only last month,” he said.

“We’ve very pleased that Mr Condo has been apprehended and we will be seeking him to be extradited to face justice in WA when that’s available.”